Influence of fasting versus protocol of carbohydrate and protein supplementation on respiratory and peripheral muscle strength: A randomized, cross-over study with healthy volunteers
Abstract
Objective: To evaluate fatigue and strength muscle respiratory and peripheral in healthy adults fasted for 12 hours or supplementation protocol containing carbohydrates and proteins. Materials and methods: A randomized cross-over clinical trial was conducted, with 15 healthy male volunteers, with normal IMC and age between 20 and 30 years. The volunteers underwent assessment of muscle function tests after an overnight fast of 12 hours, and after the supplementation period of carbohydrates and protein 2 hours before testing. The interval between the two protocols were about 2 to 4 weeks. Results: The results of peripheral muscle strength were higher after the supplementation protocol in both hands compared to the 12-hour fasting (p<0.004). Muscle fatigue was increased after fasting protocol for the first 4 steps of the sequence (p <0.01). Respiratory muscle strength showed higher values after nutritional supplementation protocol, though expiratory force was not statistically significant. In general, worsening of muscle function tests was to employees when the volunteers had fasted for 12 hours. Conclusion: After a period of fasting in healthy subjects occurs worsening function and overall muscle strength. The nutritional supplementation protocol improves the muscle strength and the performance of muscle function.
References
-Aguilar-Nasciemento, J.E.; Dock-Nascimento, D.B. Reducing preoperative fasting time: A trend based on evidence. World J Gastrointest Surg. Vol. 27. Núm. 2/3. p. 57-60. 2010.
-Aguilar-Nascimento, J.E.; Perrone, F.; Prado, L.I.A. Jejum pré-operatório de 8 horas ou de 2 horas: o que revela a evidência? Rev. Col. Bras.Cir. Vol. 36. Núm. 4. p. 350-352. 2009.
-Armstrong, C.A.; Oldham, J.A. A comparison of dominant and non-dominant hand strengths. J Hand Surg. Vol. 24. Núm. 4. p. 421-415. 1999.
-ATS/ERS. Statement on respiratory muscle testing. Am J Respir Crit Care Med. Vol. 166. Núm. 4. p. 518-624. 2002.
-Bicudo-Salomão, A.; Meireles, M.B.; Caporossi, C.; Crotti, P.L.R.; Aguilar-Nascimento, J.E. Impacto do projeto acerto na morbimortalidade pós-operatória em um hospital universitário. Rev Col Bras Cir. Vol. 38. Núm. 1. p. 3-10. 2011.
-Caporrino, F.A.; Faloppa, F.; Santos, J.B.G.; Réssio, C.; Soares, F.H.C.; Nakachima, L.R.; Segre, N.G. Estudo populacional de força de preensão palmar com dinamômetro Jamar. Rev Bras Ortop. Vol. 33. Núm. 2. p. 150-154. 1998.
-Correia, M.I. T.D.; Silva, R.G. Paradigmas e evidências da nutrição peri-operatória. Rev. Col. Bras. Cir. Vol. 32. Núm. 6.p. 342-347. 2005.
-Di Fronzo, L.A.; Yamin, N.; Patel, K.; O'Connell, T.X. Benefits of early feeding and early hospital discharge in elderly patients undergoing open colon resection. J Am Coll Surg. Vol. 197. Núm. 5. p. 747-752. 2006.
-Feguri, G.R.; Lima, P.R.L.; Lopes, A.M.; Roledo, A.; Marchese, M.; Trevisan, M.; Ahmad, H.; Baranhuk, F.; Aguilar-Nascimento, J.E. Resultados clínicos e metabólicos da abreviação do jejum com carboidratos na revascularização cirúrgica do miocárdio. Rev bras cir cardiovasc. Vol. 27. Núm. 1. p. 7-17. 2012.
-Gastaldi, A.C.; Magalhães, C.M.B.; Baraúna, M.A.; Silva, E.M.C.; Souza, H.C.D. Beneficios da cinesioterapia respiratória no pós-operatorio de colecistectomia laparoscópica. Rer Bras Fisioter. Vol. 12. Núm. 2. p. 100-106. 2008.
-Henriksen, M.G.; Hessov, I.; Dela, F.; Hansen, H.V.; Haraldsted, V.; Rodt, S.A. Effects of preoperative oral carbohydrates and peptides on postoperative endocrine response, mobilization, nutrition and muscle function in abdominal surgery. Acta Anaesthesiol Scand. Vol. 47. Núm. 2. p. 191-199. 2003.
-Luna-Heredia, E.; Martin-Peña, G.; Ruiz-Galiana, J. Handgrip dynamometry in healthy adults. Clin Nutr. Vol. 24. Núm. 2. p. 250-258.2005. 2005.
-Novais, R.D.; Miranda, A.S.; Silva, J.O.; Tavares, B.V.F.; Dourado. V. Z. Equações de referência para a predição da força de preensão manual em brasileiros de meia idade e idosos. Fisioter Pesq. Vol. 16. Núm. 3. p. 217-22. 2009.
-Nygren, J. The Metabolic Effects of Fasting and Surgery. Best Pract Res Clin Anaesthesiol. Vol. 20. Núm. 3. p. 429-438. 2006.
-Paisani, D.M.; Chiavegato, L.D.; Faresin, S.M. Volumes, capacidades pulmonares e força muscular respiratória no pós-operatório de gastroplastia. J Bras Pneumol.Vol. 31. Núm. 2. p. 125-132. 2005.
-Perrone, F.; Silva-Filho, A.C.; Adôrno, I.F.; Anabuki, N.T.; Leal, F.S.; Colombo, T.; Silva, B.D.; Dock-Nascimento, D.B.; Damião, A.; Aguilar-Nascimento, J.E. Effects of preoperative feeding with a whey protein plus carbohydrate drink on the acute phase response and insulin resistance. A randomized trial. Nutrition Journal. Vol. 10. Núm. 66. p. 2-7. 2011.
-Practice guidelines for preoperative fasting and the use of pharmacological agents to reduce the risk of pulmonary aspiration: application to healthy patients undergoing elective procedures: a report by the American Society of Anaesthesiologists Task Forceon Preoperative Fasting. Anesthesiology. Vol. 90. Núm. 3. p. 896-905. 1999.
-Santos, K.M.S.; Cerqueira, Neto. M.L.; Carvalho, V.O.; Santana Filho, V.J.; Silva, W.M.; AraújoFilho, A.F.; Cerqueira, T.C.F.; Cacau, L.A.P. Avaliação da força muscular periférica de pacientes submetidos a cirurgia cardíaca eletiva: um estudo longitudinal. Rev Bras Cir Cardiovasc. Vol. 29. Núm. 1. p. 125-136. 2013.
-Schlussel, M.M.; Anjos, L.A.; Kak, G. A. Dinamometria manual e seu uso na avaliação nutricional. Rev Nutr. Vol. 21. Núm. 2. p. 223-235. 2008.
-Silva, F.A.; Lopes, T.M.; Duarte, J.; Medeiros, R.F. Physiotherapeutic treatment in postoperative of laparotomy. J Health Sci Inst. Vol. 28. Núm. 4. p. 341-4. 2010.
-Soop, M.; Nygren, J.; Myrenfors, P.; Thorell, A.; Ljungqvist, O. Preoperative oral carbohydrate treatment attenuates immediate postoperative insulin resistance. Am J Physiol Endocrinol Metab. Vol. 280. p. E576-E583. 2001.
-Soreide, E.; Eriksson, L.I.; Hirlekar, G.; Eriksson, H.; Henneberg, S.W.; Sandin, R.; Raeder, J. Pre-operative fasting guidelines: an update. Acta Anaesthesiol Scand. Vol. 49. Núm. 8. p. 1041-1047. 2005.
-Weimann, A.; Braga, M.; Harsanyi, L.; Laviano, A.; Ljungqvist, O.; Soeters, P.; German Society for Nutritional Medicine-DGEM, Jauch, K.W.; Kemen, M.; Hiesmayr, J.M.; Horbach, T.; Kuse, E.R.; Vestweber, K.H. European Society for Parenteral and Enteral Nutrition-ESPEN. ESPEN Guidelines on enteral nutrition: surgery including organ transplantation. Clin Nutr. Vol. 25. Núm. 2. p. 224-244. 2006.
-Wang, X.; Hu, Z.; Hu, J.; Du, J.; Mitch, W.E. Insulin Resistance Accelerates Muscle Protein Degradation: Activation of the Ubiquitin-Proteasome Pathway by Defects in Muscle Cell Signaling. Endocrinol. Vol.147. Núm. 9. p. 4160-4168. 2006.
-Young, V.L.; Pin, P.; Kraemer, B.A.; Gould, R.B.; Nemergut, L.; Pellowski, M. Fluctuation in grip strength and pinch strength among normal subjects. J Hand Surg. Vol. 14a. Núm. 1. p. 125-129. 1989.
Authors who publish in this journal agree to the following terms:
- Authors retain the copyright and grant the journal the right of first publication, with work simultaneously licensed under the Creative Commons Attribution License BY-NC which allows the sharing of the work with acknowledgment of the authorship of the work and initial publication in this journal.
- Authors are authorized to enter into additional contracts separately for non-exclusive distribution of the version of the work published in this journal (eg, publishing in institutional repository or book chapter), with acknowledgment of authorship and initial publication in this journal.
- Authors are allowed and encouraged to post and distribute their work online (eg, in institutional repositories or on their personal page) at any point before or during the editorial process, as this can bring about productive change as well as increase impact and impact. citation of published work (See The Effect of Free Access).
