Baixa dose de Whey Protein reduz glicose, triglicérides e controla o peso corporal em ratos Wistar

Jaqueline Maisa Franzen; Juliano Graciano Vaz; Vilmair Zancanaro; Rafael Mariano de Bitencourt

Jaqueline Maisa Franzen Universidade Alto Vale do Rio do Peixe
Juliano Graciano Vaz Universidade Alto Vale do Rio do Peixe
Vilmair Zancanaro Universidade Alto Vale do Rio do Peixe
Rafael Mariano de Bitencourt Universidade Alto Vale do Rio do Peixe. Universidade do Oeste de Santa Catarina

Keywords: Protein diet, Cafeteria diet, Obesity, Metabolic syndrome

Abstract

Objective: The increasing incidence of obesity and metabolic diseases are the consequence of unbalanced diet.In this study, we evaluated the influence of low dose of whey protein concentrate (WPC) and cafeteria diet (CAF) on metabolic and biochemical parameters in rats. Methods: Wistar rats were divided into 3 groups: control group with standard diet (CTL), low dose of WPC (WPD) and cafeteria diet (CAF), diets were offered for 8 weeks. The body weight values, epididymal fat, Lee's index, glucose, triglycerides, total cholesterol and fractions, urea, creatinine, AST and ALT were measured. Results: There was significant reduction in glucose (P<0.05), triglycerides (P<0.01), body weight control and there was no increase in the Lee Index in the group (P>0.05) WPD. The CAF group showed the opposite result WPD group, a significant increase in glucose (P<0.05) enhanced weight gain (P<0.001) increase in Lee index (P <0.001), higher in relation to the epididymal fat CTL group (P<0.01) and WPD (P<0.001). The values of the index Lee, epididymal fat, glucose and triglycerides were lower in the group that the WPD CAF group at the end of treatment. Discussion: whey proteins have great potential to control or prevent diseases such as diabetes and severe obesity. The values of the index Lee, epididymal fat, glucose and triglycerides were lower in the group that the WPD CAF group at the end of treatment. Conclusion: Our results show that low doses of WPC are effective in reducing blood glucose, triglycerides, control body weight, and can be used with nutritional alternative in obese, overweight or normal for preventing or controlling metabolic disorders.

Author Biographies

Jaqueline Maisa Franzen, Universidade Alto Vale do Rio do Peixe

Graduanda do Curso de Farmácia da Universidade Alto Vale do Rio do Peixe; Departamento de Farmácia

Juliano Graciano Vaz, Universidade Alto Vale do Rio do Peixe

Educardor Físico, Especialista em Fisiologia do Exercício.

Vilmair Zancanaro, Universidade Alto Vale do Rio do Peixe

Farmacêutica, Especialista em Análises Clínicas; Mestranda em Ciências e Biotecnologia pela Universidade do Oeste de Santa Catarina

Rafael Mariano de Bitencourt, Universidade Alto Vale do Rio do Peixe. Universidade do Oeste de Santa Catarina

Doutor em Farmacologia pela Universidade Federal de Santa Catarina - UFSC

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Low dose of whey protein reduces of glucose, triglycerides and body weight control in rats wistar

Abstract

Author Biographies

References