Potential obesogenic effects of interesterified fat present in processed foods

  • Bruna Alonso Martins Nutricionista - HCFMUSP, aluna do curso de Especialização em Nutrição Esportiva e Obesidade, Departamento de Ciências da Saúde, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto-SP, Brasil.
  • Cristiana Araújo Gontijo Doutora em Ciências da Saúde - UFU, Docente da Ânima Educação, Departamento de Ciências da Saúde, Uberlândia-MG, Brasil.
  • Cristina Matos Boaventura Mestre em Fisioterapia Cardiorrespiratória - UNITRI, Docente da Ânima Educação, Departamento de Ciências da Saúde, Uberlândia-MG, Brasil.
  • Léia Cardoso de Sousa Doutora em Ciências da Saúde - UFU, Docente da Ânima Educação, Departamento de Ciências da Saúde, Uberlândia-MG, Brasil.
  • Phelipe Elias da Silva Cirurgião-dentista, Docente da Ânima Educação, Departamento de Saúde Coletiva. Uberlândia-MG, Brasil.
  • Heitor Bernardes Pereira Delfino Doutor em Medicina Clínica Médica - FMRP/USP, Docente do Curso de Especialização em Nutrição Esportiva e Obesidade, Departamento de Ciências da Saúde, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto-SP, Brasil.
Keywords: Interesterification, Obesity, Processed foods

Abstract

Introduction: Given the current scenario of disuse of partially hydrogenated vitamins by the industry, the use of interesterified vitamins and their consumption by the population has increased in recent years. However, the metabolic effects of interesterification in the organism are still not completely elucidated. Objective: To discuss the effects of interesterified vitamins on body composition through an integrative literature review. Materials and Methods: The articles were searched in the Pubmed/Scielo/Lilacs databases and selected according to the inclusion criteria: original articles that evaluated, in rodents or humans, the effect of consumption of interesterified fat on body composition. Results: 14% (2) of the included studies were with humans and 86% (12) with rodents. The fat sources used in the experimental protocols were different, with 29% (4) fats rich in palmitic or stearic acids and 29% (4) via palm oil, in addition to the study of other types of lipid sources (43% - 6). Conclusion: The results indicate that interesterified fat can promote changes in body composition. However, the results are still inconclusive and further studies in the area, with similar protocols that facilitate comparisons, are needed to elucidate the obesogenic effect of consuming interesterified information.

References

-ANVISA. Ácidos graxos trans: Documento de base para discussão regulatória, 2018. RDC N°332 de 23 de dezembro de 2019. Vol. 2019. p. 4-5.

-Afonso, M.S.; e colaboradores. Dietary interesterified fat enriched with palmitic acid induces atherosclerosis by impairing macrophage cholesterol efflux and eliciting inflammation. Journal of Nutritional Biochemistry. Vol. 32. 2016. p. 91-100.

-Cho, Y.Y.; e colaboradores. Differential effect of corn oil-based low trans structured fat on the plasma and hepatic lipid profile in an atherogenic mouse model: Comparison to hydrogenated trans fat. Lipids in Health and Disease. Vol. 10. Num. 1. 2011. p. 1-15.

-Filippou, A.; e colaboradores. Palmitic acid in the sn-2 position decreases glucose-dependent insulinotropic polypeptide secretion in healthy adults. European Journal of Clinical Nutrition. Vol. 68. Num. 5. 2014. p. 549-554.

-Gouk, S. W.; e colaboradores. Long-chain SFA at the sn-1, 3 positions of TAG reduce body fat deposition in C57BL/6 mice. British Journal of Nutrition. Vol. 110. Num. 11. 2013. p. 1987-1995.

-Lavrador, M.S.F.; e colaboradores. Interesterified fats induce deleterious effects on adipose tissue and liver in LDLr-KO mice. Nutrients. Vol. 11. Num. 2. 2019. p. 1-16.

-Lee, Y.Y.; e colaboradores. Short term and dosage influences of palm based medium- and long-chain triacylglycerols on body fat and blood parameters in C57BL/6J mice. Food and Function. Vol. 5. Num. 1. 2014. p. 57-64.

-Lee, Y.Y.; e colaboradores. Structural difference of palm based Medium- and Long-Chain Triacylglycerol (MLCT) further reduces body fat accumulation in DIO C57BL/6J mice when consumed in low fat diet for a mid-term period. Food Research International. Vol. 103. 2018. p. 200-207.

-Ministério da Saúde. Guia Alimentar para a População Brasileira. Ministério da Saúde. Vol. 2. 2014. p. 1-158.

-Ministério da Saúde. Vigilância de fatores de risco e proteção para doenças crônicas por inquérito telefônico. Brasília: Vigitel. Vol. 1. 2018. p. 1-132.

-Miyamoto, J.E.; e colaboradores. Interesterified palm oil impairs glucose homeostasis and induces deleterious effects in liver of Swiss mice. Metabolism. Vol. 112. 2020.

-Miyamoto, J.E.; e colaboradores. Interesterified soybean oil promotes weight gain, impaired glucose tolerance and increased liver cellular stress markers. Journal of Nutritional Biochemistry. Vol. 59. 2018. p. 153-159.

-Moreira, D.K.T.; e colaboradores. Evaluation of structured lipids with behenic acid in the prevention of obesity. Food Research International. Vol. 95. 2017. p. 52-58.

-Nagaraju, A.; Lokesh, B.R. Rats fed blended oils containing coconut oil with groundnut oil or olive oil showed an enhanced activity of hepatic antioxidant enzymes and a reduction in LDL oxidation. Food Chemistry. Vol. 108. Num. 3. 2008. p. 950-957.

-Ng, Y.T.; e colaboradores. Interesterified palm olein (Iepalm) and interesterified stearic acid-rich fat blend (IEStear) have no adverse effects on insulin resistance: a randomized control trial. Nutrients. Vol. 10. Num. 1112. 2018. p. 1-16.

-Organização Pan Americana de Saúde. Obesidade entre crianças e adolescentes aumentou dez vezes em quatro décadas, revela novo estudo do Imperial College London e da OMS. Brasília: Banco de Notícias. 2017.

-Reena, M.B.; Lokesh, B.R. Hypolipidemic effect of oils with balanced amounts of fatty acid obtained by blending and interesterification of coconut oil with rice bran oil or sesame oil. Journal of Agricultural and Food Chemistry. Vol. 55. Num. 25. 2007. p. 10461-10469.

-Revoredo, C.M.S.; Araújo, C.G.B.; Silva, D.F.S.; Rocha, J.K.D. Implicações nutricionais que os ácidos graxos trans exercem na saúde da população: análise reflexiva nutricional. Rev Enferm UFPE. Vol. 11. Num. 2. 2017. p. 731-735.

-Salve, M.G.C. Obesidade e peso corporal: riscos e consequências. Espírito Santo de Pinhal: Movimento & Percepção. Vol. 6. Num. 8. 2006. p. 29-48.

-Sakono, M.; e colaboradores. Absorption and lymphatic transport of interesterified or mixed fats rich in saturated fatty acids and their effect on tissue lipids in rats. Nutrition Research. Vol. 17. Num. 7. 1997. p. 1131-1141.

-Tholstrup, T.; e colaboradores. Effect of 6 dietary fatty acids on the postprandial lipid profile, plasma fatty acids, lipoprotein lipase, and cholesterol ester transfer activities in healthy young men. American Journal of Clinical Nutrition. Vol. 73. Num. 2. 2001. p. 198-208.

-Vigitel. Ministério da Saúde. RDC N°332. Agência Nacional de Vigilância Sanitária, 26 de dezembro de 2019.

-Zsinka, A.J.; e colaboradores. Effect of interesterified dietary fat mixtures on various lipid indices and liver metal content of rats in fat-metabolism disturbance. Die Nahrung. Vol. 32. Num. 9. 1988. p. 815-821.

Published
2024-06-20
How to Cite
Martins, B. A., Gontijo, C. A., Boaventura, C. M., Sousa, L. C. de, Silva, P. E. da, & Delfino, H. B. P. (2024). Potential obesogenic effects of interesterified fat present in processed foods. Brazilian Journal of Obesity, Nutrition and Weight Loss, 18(114), 661-668. Retrieved from https://www.rbone.com.br/index.php/rbone/article/view/2444
Section
Scientific Articles - Review

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