Does nutritional status interferes with the quality of life of children and adolescents with cystic fibrosis: a cross-sectional study
Abstract
Introduction: Nutrition plays an essential role in the survival and quality of life (QOL) of patients with cystic fibrosis (CF). Objective: This study aims to assess the relationship between nutritional status and QOL in children and adolescents with CF. Materials and methods: It is a cross-sectional study that analyzed patients aged 2 to 14 years with CF between May 2019 and March 2020. We analyzed sociodemographic data, clinical characteristics, nutritional status, and QOL by using the Cystic Fibrosis Questionnaire and Pediatric Quality of Life Inventory. Patients were divided into two groups by body mass index (BMI < or ≥ 50th percentile). Discussion: Periodic monitoring of nutritional status should be part of the routine of CF patients, being essential to prevent the decline in clinical status and QOL. Results: 81 patients participated in the study, 56.8% male, 87.7% white; 41.3% were in the BMI ≥ 50th percentile. When comparing the QOL domains concerning the BMI percentile, we observed a statistical difference in the domains of eating and weight for children aged 6 to 11 years. As for the domains of body image and eating, the participants were 12/13-year-old adolescents who’s those in the BMI <50th percentile, obtained the lowest score. There was an association between QOL with age, sex, nutritional status, and clinical variables of CF patients. Conclusion: Patients who were at BMI <50th percentile obtained the lowest scores in the domains of eating, weight, and body image, supporting the hypothesis that nutritional status negatively affects QOL, especially in these domains.
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