Review of the effects of consumption of linseed on liver and lipid profile

  • Poliana dos Santos Conde Departamento de Ciências da Natureza, Campus Universitário de Rio das Ostras, Universidade Federal Fluminense (UFF), Rio das Ostras, Rio de Janeiro, Brasil.
  • Marcos Roberto de Oliveira Departamento de Bioquí­mica, Universidade Federal do Rio Grande do Sul (UFRS), Porto Alegre, Rio Grande do Sul, Brasil.
  • Flavia Bittencourt Brasil Departamento de Ciências da Natureza, Campus Universitário de Rio das Ostras, Universidade Federal Fluminense (UFF), Rio das Ostras, Rio de Janeiro, Brasil.
Keywords: Linseed, Liver, lipid profile

Abstract

Introduction: Flaxseed is a functional food rich in fiber, omega-6 / omega-3, protein, minerals and vitamins, as well as phytoestrogens such as lignans. It has anti-inflammatory property and analgesic activity, and has important effects on immune responses due to its trace elements. Materials and Methods: This is a review that goals to understand the effects of flaxseed consumption on the lipid profile and liver. After applying inclusion and exclusion criteria, 19 studies found in the Medline, SciELO and CINAHL databases were analyzed. Discussion: Alpha linolenic acid (ALA) present in flaxseed is associated with improved lipid profile. In addition to the liver, studies show the antioxidant activity of flaxseed in other organs. Flaxseed anti-inflammatory activity appears to be linked to liver protection with preservation of architecture and suppression of liver enzyme increase, even under hostile conditions. Results and conclusion: The effect of flaxseed was analyzed on the following parameters: lipid profile, prevention of liver damage, morphological parameters and impact of flaxseed consumption in different pathologies. Flaxseed consumption improved the lipid profile, reduced oxidative stress and expression of inflammatory mediators in the liver, in addition to preserving the liver architecture and severity of changes already established by aggressions such as alcohol intake and high fat diets. In addition, ingestion of isolated flaxseed did not cause any liver alteration, answering the main question of this review.

Author Biographies

Poliana dos Santos Conde, Departamento de Ciências da Natureza, Campus Universitário de Rio das Ostras, Universidade Federal Fluminense (UFF), Rio das Ostras, Rio de Janeiro, Brasil.

Graduanda em Enfermagem no Campus Universitário de Rio das Ostras da Universidade Federal Fluminense.

Marcos Roberto de Oliveira, Departamento de Bioquí­mica, Universidade Federal do Rio Grande do Sul (UFRS), Porto Alegre, Rio Grande do Sul, Brasil.

Professor pós-doutor em Bioquí­mica; Possui experiência em pesquisas com  suplementação aguda e crônica com moléculas bioativas, função mitocondrial e estresse oxidativo, entre outros; é membro do corpo editorial de diversos periódicos internacionais.

Flavia Bittencourt Brasil, Departamento de Ciências da Natureza, Campus Universitário de Rio das Ostras, Universidade Federal Fluminense (UFF), Rio das Ostras, Rio de Janeiro, Brasil.

Professora de Histologia e Embriologia do Campus Universitário de Rio das Ostras da  Universidade Federal Fluminense, ní­vel associado; Doutora em Biologia Humana e Experimental, atua em linha de pesquisa relacionada a diferenteos modelos nutricionais como desnutrição, suplementação com ácido fólico e linhaça. 

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Published
2020-10-18
How to Cite
Conde, P. dos S., Oliveira, M. R. de, & Brasil, F. B. (2020). Review of the effects of consumption of linseed on liver and lipid profile. Brazilian Journal of Obesity, Nutrition and Weight Loss, 14(86), 519-529. Retrieved from https://www.rbone.com.br/index.php/rbone/article/view/1285
Issue
Vol. 14 No. 86 (2020)
Section
Scientific Articles - Review

Copyright (c) 2020 Poliana dos Santos Conde, Marcos Roberto de Oliveira, Flavia Bittencourt Brasil

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